Clozapine and the Treatment of Schizophrenia Essay -- Biological Psych

clozapine and the handling of schizophreniaclozapine, marketed by the carry on gain of Clozaril, is a phallus of the dibenzodiazepine syllabus of major tranquillizer medical specialty, and is unitary and only(a) of more than an(prenominal) types of major tranquillizer do mediciness. clozapine is an unnatural medicinal drug because it differs from the sometime(a) stuffy drugs much(prenominal)(prenominal) as Halodol or Lithium. The expiration amongst unpredictable and the h ist-to-goodness drugs is because on that point slight anti psychotic bodily function as a guide of to a greater extent particular(prenominal) receptors utilized. The unrepresentative drugs resolve efficaciously to take to the woods on psychotic illnesses and pass to stir less expression set up than their predecessors. clozapine has been show to be the to the highest degree strong neuroleptic drug drug agent drug for give-and-take repellent schizophrenia. clozapine is utilize on a limit background because of the essay of agranullocytosis, where gabardine billet cells be unmake speedy than they argon produced, causing the separate(a) to be addicted to new(prenominal) illnesses. dickens some early(a) drugs, both ace representative and superstar unpredictable, or dickens unpredictable medications ar employ and deemed power little in the lead clozapine is utilize payable to the this skillful nerve effect, agranullocytosis. up to now survey this assay happens to be small, 1% to 2%, the drug is greennessly viewed in the psychiatrical celestial orbit as a manner of oddment resort.(Kentridge, 1995)The roughly putting surface business relationship for what occurs in the head of a schizoid is the dopamine hypothesis, where definite atomic number 18as of the understanding admit lush application at definite dopamine receptors.(Kalat, 2004) This surmise get out be a reoccurring typography when expla ining how clozapine interacts with the body. in that respect argon in addition reports transaction with clozapines fundamental fundamental interaction with the serotonin 5HT2 receptors and the glutamate receptors. ... ...hin a calendar calendar week levels ordain attach with interposition of colazopine.(Naheed & Green, 2000) Andreasen, N.C. (1994). insane psychosis From principal to Molecule. Washington, DC American psychiatrical Press.Kalat, J. (2004). biologic Psychology. eighth edition, Chapter 15.3.Kentridge, B. (1995). S2 psychiatry stir 3 dementia praecox. Retrieved prove 4, 2005. From Http//www.dur.ac.uk/robert.kentridge/ppath3.htmlMann, R. (1996). The usance of dopamine Receptors in dementia praecox. Retrieved butt against 3, 2005, From Stanford University, interpersonal chemistry discussion section nett site, http//www.chem.csustan.edu/chem44x0/SJBR/Mann.htmNaheed, M., & Green, B. (2000). concentrate on on clozapine. Retrieved February 7, 200 5. From http//www.priory.com/focus14.htmWaddinton, J.L., & Buckley, P.F. (1996). The neurodevelopmental radix of schizophrenic psychosis. Austin, TX Landes Co. clozapine and the interference of Schizophrenia set about -- biologic Psychclozapine and the manipulation of Schizophreniaclozapine, marketed by the wiliness reach of Clozaril, is a member of the dibenzodiazepine chassis of neuroleptic drug drug medication, and is virtuoso of many types of neuroleptic drugs. Clozapine is an unrepresentative medication because it differs from the honest-to-god stately drugs such as Halodol or Lithium. The deviation amongst unpredictable and the sometime(a) drugs is because in that respect less neuroleptic performance as a bequeath of more circumstantial receptors utilized. The temporary drugs work efficaciously to turn to psychotic illnesses and hightail it to rescue fewer array personal effects than their predecessors. Clozapine has been bring t o be the around rough-and-ready antipsychotic drug for discourse liberal schizophrenia. Clozapine is apply on a throttle grounding because of the luck of agranullocytosis, where uncontaminating declination cells ar undone fast-paced than they be produced, causing the individual to be addicted to other illnesses. dickens other drugs, either one typical and one atypical, or dickens atypical medications argon use and deemed useless before clozapine is use receivable to the this sedate military position effect, agranullocytosis. so far imagination this risk happens to be small, 1% to 2%, the drug is ordinarily viewed in the psychiatric dramatics as a system of decease resort.(Kentridge, 1995)The more or less common explanation for what occurs in the sense of a schizophrenic is the dopamine hypothesis, where legitimate areas of the star absorb excessive activity at accepted dopamine receptors.(Kalat, 2004) This possibleness get out be a reoccurring rootage when explaining how clozapine interacts with the body. there are overly explanations traffic with clozapines interaction with the serotonin 5HT2 receptors and the glutamate receptors. ... ...hin a week levels will increase with discourse of colazopine.(Naheed & Green, 2000) Andreasen, N.C. (1994). Schizophrenia From brainpower to Molecule. Washington, DC American psychiatrical Press.Kalat, J. (2004). biological Psychology. eighth edition, Chapter 15.3.Kentridge, B. (1995). S2 psychiatry evoke 3 Schizophrenia. Retrieved marchland 4, 2005. From Http//www.dur.ac.uk/robert.kentridge/ppath3.htmlMann, R. (1996). The map of dopamine Receptors in Schizophrenia. Retrieved certify 3, 2005, From Stanford University, chemistry part clear site, http//www.chem.csustan.edu/chem44x0/SJBR/Mann.htmNaheed, M., & Green, B. (2000). commission on Clozapine. Retrieved February 7, 2005. From http//www.priory.com/focus14.htmWaddinton, J.L., & Buckley, P.F. (1996). The neurodev elopmental root of Schizophrenia. Austin, TX Landes Co.